The Cashew tree (Anacardium occidentale) belongs to the family Anacardiaceae. With about 18% the fraction of proteins in cashew seed is very high. Some of these proteins, like the vicilin Ana o 1, the legumin Ana o 2 and the albumin Ana o 3 are known to elicit an allergenic response. Many of the proteins are heat resistant making them stable to different production processes. For this reason cashew represents an important food allergen. Pistachio (Pistacia vera) belongs to the family of Anacardiaceae. At approximately 21%, the protein fraction in pistachio seed is very high. Some of these proteins, for example the 2S albumin Pis v 1, the 11S globulin Pis v 2 or the 7S vicillin Pis v 3 are known to be allergenic. Many of the proteins are heat stable making them resistant to different production processes. For this reason pistachio represents an important food allergen.